Cloning of a cDNA Encoding Chitotriosidase, a Human Chitinase Produced by Macrophages

Rolf G. Boot, G. Herma Renkema, Anneke Strijland, +2

Journal of Biological Chemistry

Characterization of human phagocyte-derived chitotriosidase, a component of innate immunity

Marco van Eijk, Cindy P. A. A. van Roomen, G. Herma Renkema, +7

International Immunology

Innate Immune SystemImmunologyInnate ImmunityImmune SystemInflammation +14

Chitin Recognition via Chitotriosidase Promotes Pathologic Type-2 Helper T Cell Responses to Cryptococcal Infection

Darin L. Wiesner, Charles A. Specht, Chrono K. Lee, +11

PLoS Pathogens

Chitin RecognitionMicrobial PathogensChitin AbundancePathogenesisImmunology +12

Cerebrospinal fluid biomarkers as a measure of disease activity and treatment efficacy in relapsing‐remitting multiple sclerosis

Lenka Novakova, Markus Axelsson, Mohsen Khademi, +6

Journal of Neurochemistry

Chitinase enzyme activity in CSF is a powerful biomarker of Alzheimer disease

Masami Watabe‐Rudolph, Zhangfa Song, Ludwig Lausser, +12

Neurology

Chitotriosidase gene expression in Kupffer cells from patients with non-alcoholic fatty liver disease

Lucia Malaguarnera

Gut

Chitinase 1 Is a Biomarker for and Therapeutic Target in Scleroderma-Associated Interstitial Lung Disease That Augments TGF-β1 Signaling

Chun Geun Lee, Erica L. Herzog, Farida Ahangari, +8

The Journal of Immunology

Acute Lung InjurySsc PatientsInflammatory Lung DiseaseAdvanced Lung DiseaseLung Inflammation +21

Modelling Coral Reef Futures to Inform Management: Can Reducing Local-Scale Stressors Conserve Reefs under Climate Change?

Georgina G. Gurney, Jess Melbourne-Thomas, Rollan C. Geronimo, +2

PLoS ONE

EngineeringCoral EcosystemsOcean Space UtilizationCoral Reef FuturesCoral Reef Degradation +14

Crystal Structures of Allosamidin Derivatives in Complex with Human Macrophage Chitinase

Francesco Rao, Douglas R. Houston, Rolf G. Boot, +3

Journal of Biological Chemistry

Lung Chitinolytic Activity and Chitotriosidase Are Elevated in Chronic Obstructive Pulmonary Disease and Contribute to Lung Inflammation

S. Létuvé, Alexander Kozhich, Alison A. Humbles, +8

American Journal Of Pathology

InflammationInflammatory Lung DiseaseAdvanced Lung DiseaseLung InflammationMedicine +7