Minocycline through attenuation of oxidative stress and inflammatory response reduces the neuropathic pain in a rat model of chronic constriction injury.

A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man

Gary J. Bennett, Yuanyu Xie · Pain · 1988 · 5.3K citations

Pain Disorders, Acute Pain, Pain Medicine +25

Blockade of Microglial Activation Is Neuroprotective in the 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Mouse Model of Parkinson Disease

Du Chu Wu, Vernice Jackson‐Lewis, Miquel Vila et al. · Journal of Neuroscience · 2002 · 1.2K citations · Full text

Neurodegenerative Diseases, Nigrostriatal Dopaminergic Neurons, Nigrostriatal Dopaminergic Pathway +15

Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice

Shan Zhu, Irina G. Stavrovskaya, Martin Drozda et al. · Nature · 2002 · 1.1K citations

Neurodegenerative Diseases, Amyotrophic Lateral Sclerosis, Medicine +7

A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic window

Juha Yrjänheikki, Tiina Tikka, Riitta Keinänen et al. · Proceedings of the National Academy of Sciences · 1999 · 1K citations · Full text

Cerebrovascular Disease, Pharmacotherapy, Focal Cerebral Ischemia +23

Minocycline attenuates lipopolysaccharide (LPS)-induced neuroinflammation, sickness behavior, and anhedonia

Christopher J. Henry, Yan Huang, Angela Wynne et al. · Journal of Neuroinflammation · 2008 · 641 citations · Full text