Concepedia

Astragaloside IV protects blood-brain barrier integrity from LPS-induced disruption via activating Nrf2 antioxidant signaling pathway in mice

Hongli Li, Ping Wang, Fei Huang, Jinmei Jin, Hui Wu, Beibei Zhang, Zhifei Wang, Hailian Shi, Xiaojun Wu

Toxicology and Applied Pharmacology · 2017 · 125 citations · 37 references

DOI

Concepts

References

37

Systemic LPS causes chronic neuroinflammation and progressive neurodegeneration

Liya Qin, Xuefei Wu, Michelle L. Block et al. · Glia · 2007 · 2.2K citations · Full text

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Pericytes from Brain Microvessels Strengthen the Barrier Integrity in Primary Cultures of Rat Brain Endothelial Cells

Shinsuke Nakagawa, Mária A. Deli, Shinobu Nakao et al. · Cellular and Molecular Neurobiology · 2007 · 364 citations · Full text

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Nrf2 deficiency induces oxidative stress and promotes RANKL-induced osteoclast differentiation

Seungha Hyeon, Hyojung Lee, Yoohee Yang et al. · Free Radical Biology and Medicine · 2013 · 310 citations

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Amyloid Beta Induces Oxidative Stress-Mediated Blood–Brain Barrier Changes in Capillary Amyloid Angiopathy

Anna Carrano, Jeroen J.M. Hoozemans, Saskia M. van der Vies et al. · Antioxidants and Redox Signaling · 2011 · 291 citations

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Sulforaphane preconditioning of the Nrf2/HO-1 defense pathway protects the cerebral vasculature against blood–brain barrier disruption and neurological deficits in stroke

Alessio Alfieri, Salil Srivastava, Richard Siow et al. · Free Radical Biology and Medicine · 2013 · 230 citations

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