5-Fluororacil–Induced Gastrointestinal Damage Impairs the Absorption and Anticoagulant Effects of Dabigatran Etexilate

The pharmacokinetics, pharmacodynamics and tolerability of dabigatran etexilate, a new oral direct thrombin inhibitor, in healthy male subjects

Joachim Stangier, Karin Rathgen, Hildegard Stähle et al. · British Journal of Clinical Pharmacology · 2007 · 884 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +17

The Metabolism and Disposition of the Oral Direct Thrombin Inhibitor, Dabigatran, in Humans

Stefan Blech, Thomas Ebner, Eva Ludwig-Schwellinger et al. · Drug Metabolism and Disposition · 2007 · 682 citations

Pharmacy, Pharmacokinetics, Pharmacology +14

Recommended Guidelines for the Treatment of Cancer Treatment-Induced Diarrhea

Al B. Benson, Jaffer A. Ajani, Robert B. Catalano et al. · Journal of Clinical Oncology · 2004 · 631 citations

Pharmacy, Oncology, Pharmacotherapy +17

Is the pathobiology of chemotherapy-induced alimentary tract mucositis influenced by the type of mucotoxic drug administered?

Richard M. Logan, Andrea M. Stringer, Joanne M. Bowen et al. · Cancer Chemotherapy and Pharmacology · 2008 · 157 citations

Pharmacy, Oncology, Pathobiology +14

Dabigatran etexilate activation is affected by the CES1 genetic polymorphism G143E (rs71647871) and gender

Jian Shi, Xinwen Wang, Jenny‐Hoa Nguyen et al. · Biochemical Pharmacology · 2016 · 109 citations · Full text

Life Sciences, Genetics, Molecular Genetics +3