An iridium (III) complex as potent anticancer agent induces apoptosis and autophagy in B16 cells through inhibition of the AKT/mTOR pathway

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

Tim R. Mosmann · Journal of Immunological Methods · 1983 · 55.6K citations

Life Sciences, Cell Biology, Apoptosis +14

Induction of Apoptotic Program in Cell-Free Extracts: Requirement for dATP and Cytochrome c

Xuesong Liu, Caryn Naekyung Kim, Jie Yang et al. · Cell · 1996 · 5.2K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +10

Single cell gel/comet assay: Guidelines for in vitro and in vivo genetic toxicology testing

Raymond R. Tice, Eva Agurell, Diana Anderson et al. · Environmental and Molecular Mutagenesis · 2000 · 4.8K citations

Pharmacy, Genetics, Toxicology +17

Methods in Mammalian Autophagy Research

Noboru Mizushima, Tamotsu Yoshimori, Beth Levine · Cell · 2010 · 4.5K citations · Full text

Life Sciences, Biochemistry, Cell Biology +10

Platinum Compounds: a New Class of Potent Antitumour Agents

Barnett Rosenberg, Loretta Vancamp, James E. Trosko et al. · Nature · 1969 · 3.9K citations

Medicine, Medicinal Chemistry, Pharmacology +11