Concepedia

A physiologically based pharmacokinetic (PBPK) parent-metabolite model of the chemotherapeutic zoptarelin doxorubicin—integration of in vitro results, Phase I and Phase II data and model application for drug–drug interaction potential analysis

Nina Hanke, Michael Teifel, Daniel Moj, Jan‐Georg Wojtyniak, Hannah Britz, Babette Aicher, H. Sindermann, Nicola Ammer, Thorsten Lehr

Cancer Chemotherapy and Pharmacology · 2017 · 24 citations · 28 references

References

28

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

Life Sciences, Biochemistry, Chemical Kinetics +14

Basic anatomical and physiological data for use in radiological protection: reference values

J. Valentin · Annals of the ICRP · 2002 · 1.7K citations · Full text

Dentistry, Radiology, Radiation Dosimetry +16

AHFS Drug Information

Gerald K. McEvoy · Oncology Issues · 1994 · 893 citations

Pharmacy, Pharmacotherapy, Pharmacy Practice +12

Localization and Genomic Organization of a New Hepatocellular Organic Anion Transporting Polypeptide

Jörg König, Yunhai Cui, Anne T. Nies et al. · Journal of Biological Chemistry · 2000 · 523 citations · Full text

Life Sciences, Biochemistry, Genetics +12

Metformin is a Superior Substrate for Renal Organic Cation Transporter OCT2 rather than Hepatic OCT1

Naoko Kimura, Satohiro Masuda, Yuko Tanihara et al. · Drug Metabolism and Pharmacokinetics · 2005 · 357 citations

Pharmacy, Pharmacokinetics, Pharmacology +15