Publication | Closed Access
New Metabolites Produced by <i>Cylindrocarpon</i> sp. <scp>SY</scp>‐39 from a Driftwood
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Citations
18
References
2017
Year
BotanyStaphylococcus AureusSecondary MetaboliteNew Metabolites ProducedNovel CompoundsBiosynthesisCylindropyrone AAntimicrobial Drug DiscoveryBioassay-guided IsolationAntibacterial AgentAntimicrobial CompoundPharmacologyFood PreservativesPrimary MetaboliteBiologyNatural SciencesMicrobiologyAntimicrobial PharmacodynamicsPhytochemistryMedicineChemotaxonomy
Four novel compounds, cylindropyrone A (1), 10'-hydroxyilicicolinic acid D (3), cylindrolactones A (4) and B (5), together with known dihydroinfectopyrone (2) were isolated from the culture of Cylindrocarpon sp. SY-39 from a driftwood. Their structures were elucidated using 1D- and 2D-NMR spectroscopy. Compound 3 showed antimicrobial activity against Staphylococcus aureus with MIC value of 5.0 μg/mL.
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