Dye-Independent Methods Reveal Elevated Mitochondrial Mass in Hematopoietic Stem Cells

The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype

Sheng Zhou, John D. Schuetz, Kevin D. Bunting et al. · Nature Medicine · 2001 · 2.3K citations

Developmental Biology, Abc Transporter Bcrp1/abcg2, Medicine +7

Essential role for Nix in autophagic maturation of erythroid cells

Héctor Sandoval, Perumal Thiagarajan, Swapan Dasgupta et al. · Nature · 2008 · 1.1K citations · Full text

Biology, Cell Autophagy, Cell Lineage +8

Dye efflux studies suggest that hematopoietic stem cells expressing low or undetectable levels of CD34 antigen exist in multiple species

Margaret A. Goodell, Michael Rosenzweig, Hyung L. Kim et al. · Nature Medicine · 1997 · 1.1K citations

Cell Therapy, Medicine, Stem Cell Mobilization +11

The Distinct Metabolic Profile of Hematopoietic Stem Cells Reflects Their Location in a Hypoxic Niche

Tugba Simsek, Fatih Kocabaş, Junke Zheng et al. · Cell stem cell · 2010 · 1.1K citations · Full text

Hypoxic Niche, Heme Homeostasis, Medicine +13

Normal viability and altered pharmacokinetics in mice lacking mdr1-type (drug-transporting) P-glycoproteins

Alfred H. Schinkel, Ulrich Mayer, Els Wagenaar et al. · Proceedings of the National Academy of Sciences · 1997 · 937 citations · Full text

Endocrine-related Cancer, Biochemistry, Normal Viability +15