Emerging therapies for atopic dermatitis: TRPV1 antagonists

A sensory neuron–expressed IL-31 receptor mediates T helper cell–dependent itch: Involvement of TRPV1 and TRPA1

Ferda Cevikbas, Xidao Wang, Tasuku Akiyama et al. · Journal of Allergy and Clinical Immunology · 2013 · 768 citations · Full text

Life Sciences, Immunology, Physiology +12

Pharmacological blockade of the vanilloid receptor TRPV1 elicits marked hyperthermia in humans

Narender R. Gavva, James Treanor, András Garami et al. · Pain · 2008 · 518 citations

Medicine, Pharmacology, Pharmacotherapy +14

TRPV1 Mediates Histamine-Induced Itching via the Activation of Phospholipase A₂and 12-Lipoxygenase

Won‐Sik Shim, Min-Ho Tak, Mi‐Hyun Lee et al. · Journal of Neuroscience · 2007 · 458 citations · Full text

Life Sciences, Pharmacology, Physiology +17

Targeting the Neurokinin Receptor 1 with Aprepitant: A Novel Antipruritic Strategy

Sonja Ständer, Dorothee Siepmann, Ilka Herrgott et al. · PLoS ONE · 2010 · 290 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +13

Nociceptive and inflammatory effects of subcutaneous TNF α

Heidi Junger, Linda S. Sorkin · Pain · 2000 · 238 citations

Medicine, Pharmacology, Inflammation +16