Concepedia

Design, synthesis and evaluation of novel N -hydroxybenzamides/ N -hydroxypropenamides incorporating quinazolin-4(3 H )-ones as histone deacetylase inhibitors and antitumor agents

Doan Thanh Hieu, Duong Tien Anh, Tuan Minh Nguyen, Hai Pham‐The, Huong Le‐Thi‐Thu, Jisung Kim, Jong Soon Kang, Tran Khac Vu, Phan Thị Phương Dung, Sang‐Bae Han,

Bioorganic Chemistry · 2017 · 46 citations · 20 references

DOI

Concepts

References

20

New Colorimetric Cytotoxicity Assay for Anticancer-Drug Screening

Philip Skehan, Ritsa Storeng, Dominic A. Scudiero et al. · JNCI Journal of the National Cancer Institute · 1990 · 9.8K citations

, , +10

Histone Deacetylase (HDAC) Inhibitor Kinetic Rate Constants Correlate with Cellular Histone Acetylation but Not Transcription and Cell Viability

Benjamin Lauffer, Robert Mintzer, Rina Fong et al. · Journal of Biological Chemistry · 2013 · 412 citations · Full text

, , +15

HDAC inhibitors: Clinical update and mechanism-based potential

Keith B. Glaser · Biochemical Pharmacology · 2007 · 349 citations

, , +7

Multidrug-resistant phenotype of disease-oriented panels of human tumor cell lines used for anticancer drug screening.

Lin Wu, A M Smythe, Susanna Stinson et al. · PubMed · 1992 · 157 citations

, , +14

Zinc Chelation with Hydroxamate in Histone Deacetylases Modulated by Water Access to the Linker Binding Channel

Ruibo Wu, Zhenyu Lu, Zexing Cao et al. · Journal of the American Chemical Society · 2011 · 103 citations

, , +17