TanshinoneIIA enhances the chemosensitivity of breast cancer cells to doxorubicin through down-regulating the expression of MDR-related ABC transporters

Prospective identification of tumorigenic breast cancer cells

Muhammad Al‐Hajj, Max S. Wicha, Adalberto Benito‐Hernández et al. · Proceedings of the National Academy of Sciences · 2003 · 10.4K citations · Full text

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Identification of Selective Inhibitors of Cancer Stem Cells by High-Throughput Screening

Piyush B. Gupta, Tamer T. Önder, Guozhi Jiang et al. · Cell · 2009 · 2.4K citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +14

Human breast cancer cell lines contain stem-like cells that self-renew, give rise to phenotypically diverse progeny and survive chemotherapy

Christine M. Fillmore, Charlotte Kuperwasser · Breast Cancer Research · 2008 · 1K citations · Full text

Medicine, Cell Biology, Oncology +17

Growth-Inhibitory and Tumor- Suppressive Functions of p53 Depend on Its Repression of CD44 Expression

Samuel Godár, Tan A. Ince, George W. Bell et al. · Cell · 2008 · 466 citations

Medicine, Cancer Biology, Oncology +12

The anti-inflammatory activities of Tanshinone IIA, an active component of TCM, are mediated by estrogen receptor activation and inhibition of iNOS

Guanwei Fan, Xiumei Gao, Hong Wang et al. · The Journal of Steroid Biochemistry and Molecular Biology · 2009 · 192 citations

Life Sciences, Medicinal Chemistry, Pharmacology +17