The anti-inflammatory activities of Tanshinone IIA, an active component of TCM, are mediated by estrogen receptor activation and inhibition of iNOS

Phytoestrogens and Their Human Metabolites Show Distinct Agonistic and Antagonistic Properties on Estrogen Receptor   (ER ) and ER  in Human Cells

Stefan O. Mueller · Toxicological Sciences · 2004 · 542 citations · Full text

Life Sciences, Endocrinology, Pharmacology +11

Tanshinone IIA protects cardiac myocytes against oxidative stress-triggered damage and apoptosis

Jiajia Fu, Heqing Huang, Jiajun Liu et al. · European Journal of Pharmacology · 2007 · 281 citations

Life Sciences, Cardiology, Cell Biology +14

Estrogen decreases TNF gene expression by blocking JNK activity and the resulting production of c-Jun and JunD

Sunil Kumar Srivastava, M. Neale Weitzmann, Simone Cenci et al. · Journal of Clinical Investigation · 1999 · 258 citations · Full text

Life Sciences, Endocrinology, Molecular Biology +17

Potential anticancer activity of tanshinone IIA against human breast cancer

Xiujie Wang, Yuquan Wei, Shu-Lan Yuan et al. · International Journal of Cancer · 2005 · 236 citations · Full text

Medicine, Oncology, Pharmacology +13

Scavenging effects of salvia miltiorrhiza on free radicals and its protection for myocardial mitochondrial membranes from ischemia-reperfusion injury.

Baochang Zhao, Wei Jiang, Yu Zhao et al. · PubMed · 1996 · 193 citations

Life Sciences, Biochemistry, Physiology +17