Concepedia

The high-production volume fungicide pyraclostrobin induces triglyceride accumulation associated with mitochondrial dysfunction, and promotes adipocyte differentiation independent of PPARγ activation, in 3T3-L1 cells

Anthony L. Luz, Christopher D. Kassotis, Heather M. Stapleton, Joel N. Meyer

Toxicology · 2017 · 64 citations · 54 references

DOI

Concepts

References

54

Increased oxidative stress in obesity and its impact on metabolic syndrome

Shigetada Furukawa, Takuya Fujita, Michio Shimabukuro et al. · Journal of Clinical Investigation · 2004 · 5.2K citations · Full text

An Antidiabetic Thiazolidinedione Is a High Affinity Ligand for Peroxisome Proliferator-activated Receptor γ (PPARγ)

Jürgen M. Lehmann, Linda B. Moore, Tracey Smith-Oliver et al. · Journal of Biological Chemistry · 1995 · 3.6K citations · Full text

Stimulation of adipogenesis in fibroblasts by PPARγ2, a lipid-activated transcription factor

Peter Tontonoz, Erding Hu, Bruce M. Spiegelman · Cell · 1994 · 3.5K citations

, , +10

Reactive oxygen species have a causal role in multiple forms of insulin resistance

Nicholas Houstis, Evan D. Rosen, Eric S. Lander · Nature · 2006 · 2.5K citations

, , +13

Mitochondrial Dysfunction in the Elderly: Possible Role in Insulin Resistance

Kitt Falk Petersen, Douglas E. Befroy, Sylvie Dufour et al. · Science · 2003 · 2.1K citations · Full text

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