Concepedia

Genetic Predisposition, Clinical Risk Factor Burden, and Lifetime Risk of Atrial Fibrillation

Lu‐Chen Weng, Sarah R. Preis, Olivia Hulme, Martin G. Larson, Seung Hoan Choi, Biqi Wang, Ludovic Trinquart, David D. McManus, Honghuang Lin, Kathryn L. Lunetta,

Circulation · 2017 · 273 citations · 45 references

DOIFull text

Open access

Abstract

In our community-based cohort, the lifetime risk of AF was 37%. Estimation of polygenic AF risk is feasible and together with clinical risk factor burden explains a substantial gradient in long-term AF risk.

References

45

R: A Language and Environment for Statistical Computing

R Core Team · 2000 · 352.8K citations · Full text

A new look at the statistical model identification

Hirotugu Akaike · IEEE Transactions on Automatic Control · 1974 · 49.6K citations · Full text

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A Proportional Hazards Model for the Subdistribution of a Competing Risk

Jason P. Fine · Journal of the American Statistical Association · 1999 · 13.2K citations

, , +21

Second-generation PLINK: rising to the challenge of larger and richer datasets

Christopher Chang, Carson C. Chow, Laurent CAM Tellier et al. · GigaScience · 2015 · 13.1K citations · Full text

UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age

Cathie Sudlow, John Gallacher, Naomi E. Allen et al. · PLoS Medicine · 2015 · 12.5K citations · Full text

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