Synthesis and antidepressant activity of a series of arylalkanol and aralkyl piperazine derivatives targeting SSRI/5-HT1A/5-HT7

The prediction of human pharmacokinetic parameters from preclinical and in vitro metabolism data

Kaoxiang Sun · Chinese New Drugs Journal · 2005 · 764 citations

Physiologically-based Pharmacokinetic Modeling, Comprehensive Retrospective Approaches, Pharmacodynamic Modeling +16

The Prediction of Human Pharmacokinetic Parameters from Preclinical and In Vitro Metabolism Data

R. Scott Obach, James G. Baxter, Theodore E. Liston et al. · Journal of Pharmacology and Experimental Therapeutics · 1997 · 574 citations

Pharmacokinetic Modeling, Preclinical Drug Evaluation, Physiologically-based Pharmacokinetic Modeling +11

Molecular cloning and expression of a 5-hydroxytryptamine7 serotonin receptor subtype.

Yiping Shen, Frederick J. Monsma, Mark A. Metcalf et al. · Journal of Biological Chemistry · 1993 · 509 citations · Full text

Nontricyclic antidepressant agents derived from cis- and trans-1-amino-4-aryltetralins

Willard M. Welch, Allen R. Kraska, Reinhard Sarges et al. · Journal of Medicinal Chemistry · 1984 · 218 citations · Full text

Psychopharmacology, Pharmacotherapy, Molecular Pharmacology +16

Enhancement of the anti-immobility action of antidepressants by a selective 5-HT7 receptor antagonist in the forced swimming test in mice

Anna Wesołowska, E Tatarczyńska, Agnieszka Nikiforuk et al. · European Journal of Pharmacology · 2006 · 112 citations

Psychiatry, Medicine, Psychotropic Medication +10