Concepedia

A Genome-Wide Association Study Finds Genetic Associations with Broadly-Defined Headache in UK Biobank (N = 223,773)

Weihua Meng, Mark J. Adams, Harry L. Hébert, Ian J. Deary, Andrew M. McIntosh, Blair H. Smith

EBioMedicine · 2018 · 86 citations · 37 references

Open access

Abstract

Our results suggest that brain function is closely related to broadly-defined headache. In addition, we found that many psychological traits have genetic correlations with headache.

References

37

GCTA: A Tool for Genome-wide Complex Trait Analysis

Jian Yang, Sang Lee, Michael E. Goddard et al. · The American Journal of Human Genetics · 2010 · 8.9K citations · Full text

Genome-wide Association Study, Genotype-phenotype Association, Genetics +5

The International Classification of Headache Disorders, 3rd edition (beta version)

Cephalalgia · 2013 · 8.1K citations · Full text

Cluster Headache, Pain Syndrome, Psychiatry +8

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

Brendan Bulik‐Sullivan, Po‐Ru Loh, Hilary K. Finucane et al. · Nature Genetics · 2015 · 6K citations · Full text

Genome-wide Association Study, Genetic Determinant, Genotype-phenotype Association +9

An atlas of genetic correlations across human diseases and traits

Brendan Bulik‐Sullivan, Hilary K. Finucane, Verneri Anttila et al. · Nature Genetics · 2015 · 4.5K citations · Full text

Genome-wide Association Study, Genetic Determinant, Human Phenotypes +12

Functional mapping and annotation of genetic associations with FUMA

Kyoko Watanabe, Erdogan Taskesen, Arjen van Bochoven et al. · Nature Communications · 2017 · 4.3K citations · Full text