Concepedia

Excessive UBE3A dosage impairs retinoic acid signaling and synaptic plasticity in autism spectrum disorders

Xingxing Xu, Chuanyin Li, Xiaobo Gao, Kun Xia, Hui Guo, Yali Li, Zijian Hao, Lei Zhang, Daming Gao, Chenfan Xu,

Cell Research · 2017 · 131 citations · 53 references

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53

Genome-wide atlas of gene expression in the adult mouse brain

Ed S. Lein, Michael Hawrylycz, Nancy Ao et al. · Nature · 2006 · 6K citations

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DNA targeting specificity of RNA-guided Cas9 nucleases

Patrick D. Hsu, David A. Scott, Joshua A. Weinstein et al. · Nature Biotechnology · 2013 · 4.9K citations · Full text

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Synaptic, transcriptional and chromatin genes disrupted in autism

Silvia De Rubeis, Xin He, Arthur P. Goldberg et al. · Nature · 2014 · 2.9K citations · Full text

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The contribution of de novo coding mutations to autism spectrum disorder

Ivan Iossifov, Brian J. O’Roak, Stephan Sanders et al. · Nature · 2014 · 2.8K citations · Full text

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Mutations in the gene encoding the synaptic scaffolding protein SHANK3 are associated with autism spectrum disorders

Christelle M. Durand, Catalina Betancur, Tobias M. Boeckers et al. · Nature Genetics · 2006 · 1.6K citations · Full text

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