Concepedia

No genetic association detected with mepolizumab efficacy in severe asthma

Lynn D. Condreay, Mathias Chiano, Héctor Ortega, Natalie Buchan, Elizabeth C. Harris, Eugene R. Bleecker, Philip J. Thompson, Marc Humbert, Peter G. Gibson, Steven W. Yancey,

Respiratory Medicine · 2017 · 20 citations · 8 references

DOI

Concepts

References

8

An integrated map of genetic variation from 1,092 human genomes

Nature · 2012 · 8.2K citations · Full text

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A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies

Bryan Howie, Peter Donnelly, Jonathan Marchini · PLoS Genetics · 2009 · 4.1K citations · Full text

, , +17

Mepolizumab Treatment in Patients with Severe Eosinophilic Asthma

Héctor Ortega, Mark C. Liu, Ian Pavord et al. · New England Journal of Medicine · 2014 · 2.3K citations · Full text

, , +16

Mepolizumab for severe eosinophilic asthma (DREAM): a multicentre, double-blind, placebo-controlled trial

Ian Pavord, Stephanie Korn, Peter Howarth et al. · The Lancet · 2012 · 2.2K citations

, , +14

Oral Glucocorticoid-Sparing Effect of Mepolizumab in Eosinophilic Asthma

Elisabeth H. Bel, Sally E. Wenzel, Philip J. Thompson et al. · New England Journal of Medicine · 2014 · 1.6K citations

, , +17