Concepedia

The small molecule luteolin inhibits N-acetyl-α-galactosaminyltransferases and reduces mucin-type O-glycosylation of amyloid precursor protein

Feng Liu, Kai Xu, Zhijue Xu, Matilde de las Rivas, Congrong Wang, Xing Li, Jishun Lu, Yueyang Zhou, Ignacio Delso, Pedro Merino,

Journal of Biological Chemistry · 2017 · 53 citations · 45 references

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Abstract

-GalNAc glycosylation and into the molecular mechanism of luteolin-mediated ppGalNAc-T inhibition.

References

45

Precision mapping of the human O‐GalNAc glycoproteome through SimpleCell technology

Catharina Steentoft, Sergey Y. Vakhrushev, Hiren J. Joshi et al. · The EMBO Journal · 2013 · 1.4K citations · Full text

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Identification, biogenesis, and localization of precursors of Alzheimer's disease A4 amyloid protein

Andreas Weidemann, Gerhard König, Dirk Bunke et al. · Cell · 1989 · 1.2K citations

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Dynamic Glycosylation of Nuclear and Cytosolic Proteins

Lisa K. Kreppel, Melissa A. Blomberg, Gerald W. Hart · Journal of Biological Chemistry · 1997 · 740 citations · Full text

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Structure of human O-GlcNAc transferase and its complex with a peptide substrate

Michael B. Lazarus, Yunsun Nam, Jiaoyang Jiang et al. · Nature · 2011 · 461 citations

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Polypeptide GalNAc-transferase T3 and Familial Tumoral Calcinosis

Kentaro Kato, Charlotte Jeanneau, Mads A. Tarp et al. · Journal of Biological Chemistry · 2006 · 424 citations · Full text

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