Bratislavské lekárske listy/Bratislava medical journal · 2017 · 81 citations · 26 references
Veterinary MedicineImmunologyInfectious DiseasesClinical ImmunologyImmunology Of Infectious DiseasesInflammationInflammation In Infectious DiseaseInflammatory BiomarkersNeutrophil BiologyPulmonary Function AssessmentPulmonary InfectionsPulmonary InflammationBiomarkersLung Inflammation BiomarkersNeutrophil-to-lymphocyte RatioPlatelet-to-lymphocyte RatioPneumonia DiagnosisPneumonia Severity AssessmentRetrospective Case Study
PURPOSE: In our study, we aimed to evaluate neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) in patients with Community-acquired pneumonia (CAP). METHODS: This is a retrospective study consisting of 114 patients with CAP and 50 control subjects. Patients with CAP were divided into 2 groups, as inpatient and outpatient. RESULTS: The main findings of our study were that NLR, PLR and CRP levels were significantly higher in CAP than those in the control group. These biomarkers were also higher in inpatient group than outpatient group, but not statistically significant. CONCLUSION: To our knowledge, this is the first study which investigated the role of NLR and PLR as inflammatory biomarkers and the difference in inpatients and outpatients with CAP and their correlation with CRP values in children. However, larger prospective studies are needed to establish their utility as a predictor for the presence of CAP (Tab. 1, Fig. 2, Ref. 9).
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Global estimate of the incidence of clinical pneumonia among children under five years of age.
Igor Rudan, Lana Tomašković, Cynthia Boschi-Pinto et al. · PubMed · 2004 · 506 citations · Full text