UK Renal Registry 18th Annual Report: Chapter 4 Demography of Patients Receiving Renal Replacement Therapy in Paediatric Centres in the UK in 2014

Abstract

* A total of 917 children and young people under 18 years with established renal failure (ERF) were receiving treatment at paediatric nephrology centres in 2014.<br/><br/>* At the census date (31st December 2014), 79.3% of prevalent paediatric patients aged &lt;18 years had a functioning kidney transplant, 11.2% were receiving haemodialysis (HD) and 9.5% were receiving peritoneal dialysis (PD).<br/><br/>* In patients aged &lt;16 years, prevalence of ERF was 60.4 per million age related population (pmarp) and the incidence 9.4 pmarp.<br/><br/>* The most common primary renal diagnosis was renal dysplasia ± reflux, present in 32.6% of prevalent paediatric patients aged &lt;16 years.<br/><br/>* About a third of patients had one or more reported comorbidity at onset of renal replacement therapy (RRT).<br/><br/>* The improvement in rates of pre-emptive transplantation for those referred early has been maintained over the last 10 years at 37.5%, compared to 27.4% in 2000–2004.<br/><br/>* At transfer to adult services, 90.3% of patients had a functioning kidney transplant.<br/><br/>* Survival during childhood amongst children commencing RRT was the lowest in those aged less than two years compared to those aged 12 to less than 16 years with a hazard ratio of 4.1 (confidence interval 2.2–8.0), and in those receiving dialysis compared to having a functioning transplant with a hazard ratio of 6.3 (confidence interval 3.9–10.2)