HDAC2 Suppresses IL17A-Mediated Airway Remodeling in Human and Experimental Modeling of COPD

Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010

Rafael Lozano, Mohsen Naghavi, Kyle J Foreman et al. · The Lancet · 2012 · 14.3K citations · Full text

Public Health, Health Sciences, Epidemiologic Methods +16

The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells

Ivaylo I. Ivanov, Brent S. McKenzie, Liang Zhou et al. · Cell · 2006 · 5.1K citations · Full text

Life Sciences, Cell Biology, Immunology +16

The Nature of Small-Airway Obstruction in Chronic Obstructive Pulmonary Disease

James C. Hogg, Fanny Chu, Soraya Utokaparch et al. · New England Journal of Medicine · 2004 · 3.8K citations · Full text

Medicine, Clinical Sciences, Pathology +14

TGFβ in the Context of an Inflammatory Cytokine Milieu Supports De Novo Differentiation of IL-17-Producing T Cells

Marc Veldhoen, Richard J. Hocking, Christopher J. Atkins et al. · Immunity · 2006 · 3.6K citations · Full text

Life Sciences, Cell Biology, Immunology +12

Human CD25highFoxp3pos regulatory T cells differentiate into IL-17–producing cells

Hans J. P. M. Koenen, Ruben L. Smeets, Paul Vink et al. · Blood · 2008 · 726 citations · Full text

Life Sciences, Cell Biology, Immunology +14