Linc<scp>RNA</scp>‐p21 suppresses development of human prostate cancer through inhibition of <scp>PKM</scp>2

Abstract

We demonstrated that lincRNA-p21 blunted the prostate cancer cell proliferation and tumorigenic capacity through down-regulation of PKM2. Therefore, targeting PKM2 or glycolysis might be a therapeutic strategy in prostate cancer patients with lowly expressed lincRNA-p21.