Concepedia

Sequential three-component reaction of homophthalonitrile, salicylaldehydes and nitromethane

Alexey А. Festa, Olga А. Storozhenko, Delphine R Bella Ndoutoume, Leonid G. Voskressensky

Mendeleev Communications · 2017 · 14 citations · 9 references

DOI

Concepts

Abstract

An effective preparative multi-component synthesis of 12-nitromethyl-12H-chromeno[2,3-c]isoquinolin-5-amines comprised sequential reactions of salicylaldehydes with homophthalonitrile and then with nitromethane under MW irradiation.

References

9

Solvent-free cascade reaction: direct multicomponent assembling of 2-amino-4H-chromene scaffold from salicylaldehyde, malononitrile or cyanoacetate and nitroalkanes

Michaïl N. Elinson, Alexey I. Ilovaisky, Valentina M. Merkulova et al. · Tetrahedron · 2010 · 89 citations

, , +11

Highly efficient enantioselective three-component synthesis of 2-amino-4H-chromenes catalysed by chiral tertiary amine-thioureas

Gaosheng Yang, Chongrong Luo, Xiaolong Mu et al. · Chemical Communications · 2012 · 68 citations

, , +7

Synthesis and Characterization of Novel 2-Amino-Chromene-Nitriles that Target Bcl-2 in Acute Myeloid Leukemia Cell Lines

Hosadurga K. Keerthy, Manoj Garg, Chakrabhavi Dhananjaya Mohan et al. · PLoS ONE · 2014 · 61 citations · Full text

, , +13

Antimycobacterial activity of novel 1,2,4-oxadiazole-pyranopyridine/chromene hybrids generated by chemoselective 1,3-dipolar cycloadditions of nitrile oxides

Raju Ranjith Kumar, Subbu Perumal, J. Carlos Menéndez et al. · Bioorganic & Medicinal Chemistry · 2011 · 60 citations

, , +15

Pot, atom and step economic (PASE) synthesis of 5-isoxazolyl-5H-chromeno[2,3-b]pyridine scaffold

A. N. Vereshchagin, Michaïl N. Elinson, Yuliya E. Anisina et al. · Mendeleev Communications · 2015 · 54 citations

, , +10