Comparative effect of imatinib and ponatinib on autophagy and miRNome in chronic myeloid leukemia

Antisense inhibition of human miRNAs and indications for an involvement of miRNA in cell growth and apoptosis

A. M. Cheng · Nucleic Acids Research · 2005 · 1.4K citations · Full text

Life Sciences, Cancer Biology, Molecular Biology +17

A distinct “side population” of cells with high drug efflux capacity in human tumor cells

Charlotte Hirschmann-Jax, Angela E. Foster, Gerald Wulf et al. · Proceedings of the National Academy of Sciences · 2004 · 1.3K citations

Medicine, Cell Biology, Oncology +17

AP24534, a Pan-BCR-ABL Inhibitor for Chronic Myeloid Leukemia, Potently Inhibits the T315I Mutant and Overcomes Mutation-Based Resistance

Thomas O’Hare, William C. Shakespeare, Xiaotian Zhu et al. · Cancer Cell · 2009 · 1.2K citations · Full text

Medicine, Oncology, Pharmacology +9

Human chronic myeloid leukemia stem cells are insensitive to imatinib despite inhibition of BCR-ABL activity

Amie S. Corbin, Anupriya Agarwal, Marc Loriaux et al. · Journal of Clinical Investigation · 2010 · 763 citations

Medicine, Cell Biology, Oncology +17

Bcr-Abl kinase domain mutations, drug resistance, and the road to a cure for chronic myeloid leukemia

Thomas O’Hare, Christopher A. Eide, Michael W. Deininger · Blood · 2007 · 640 citations · Full text

Medicine, Cancer Biology, Oncology +16