The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis.

Daniel Fishman, Gary Faulds, Rachel Jeffery, +4

Journal of Clinical Investigation

Il-6 GenotypeImmunologyGenetic EpidemiologyIl-6 TranscriptionImmune-related Gene Polymorphism +22

Solvent Mediated Interactions in the Structure of the Nucleosome Core Particle at 1.9Å Resolution

Curt A. Davey, David F. Sargent, Karolin Luger, +2

Journal of Molecular Biology

Nucleosome Core ParticleChromatinProtein AssemblySolvent Mediated InteractionsProtein Folding +8

Nucleotide sequence of the Kaposi sarcoma-associated herpesvirus (HHV8)

James J. Russo, Roy A. Bohenzky, Ming-Cheng Chien, +8

Proceedings of the National Academy of Sciences

Ks TumorMolecular VirologyPathogenesisImmunologyPathology +10

Duration of Nuclear NF-κB Action Regulated by Reversible Acetylation

Lin‐Feng Chen, Wolfgang Fischle, Eric Verdin, +1

Science

Molecular RegulationMolecular BiologyTranscriptional RegulationSignaling PathwayCell Regulation +15

A positive role for histone acetylation in transcription factor access to nucleosomal DNA

Daniel Y. Lee, Jeffrey J. Hayes, Dmitry Pruss, +1

Cell

Histone ModificationsEpigenetic ChangeGeneticsMolecular BiologyNucleosomal Dna +15

DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci

Michael R. Rountree, Kurtis E. Bachman, Stephen B. Baylin

Nature Genetics

ChromatinTranscriptional RegulationMolecular RegulationNatural SciencesMolecular Biology +9

Control of TH2 polarization by the chemokine monocyte chemoattractant protein-1

Long Gu, Susan Tseng, Renée M. Horner, +3

Nature

Signal TransductionBiochemistryBiochemical InteractionBiomolecular InteractionMedicine +3

Systems biology approaches identify ATF3 as a negative regulator of Toll-like receptor 4

Mark Gilchrist, Vésteinn Thórsson, Bin Li, +6

Nature

InflammationToll-like ReceptorsMolecular ImmunologySignal TransductionAutoimmune Disease +13

Tet2 is required to resolve inflammation by recruiting Hdac2 to specifically repress IL-6

Qian Zhang, Kai Zhao, Qicong Shen, +13

Nature

InflammationCytokineInflammatory DiseaseImmunologyImmune Regulation +6

Stat3 Dimerization Regulated by Reversible Acetylation of a Single Lysine Residue

Zhenglong Yuan, Yingjie Guan, Devasis Chatterjee, +1

Science

Stat3 MutantWild-type Stat3Signal TransducersMolecular BiologyChemical Biology +18