Concepedia

Targeted inhibition of G<sub>q</sub>signaling induces airway relaxation in mouse models of asthma

Michaela Matthey, Richard Roberts, Alexander Seidinger, Annika Simon, R Schröder, Markus Kuschak, Suvi Annala, Gabriele M. König, Christa E. Müller, Ian P. Hall,

Science Translational Medicine · 2017 · 58 citations · 23 references

DOIFull text

Open access

Concepts

Abstract

proteins may be a useful therapeutic strategy to achieve bronchorelaxation in asthmatic lung disease.

References

23

Conventional and Monocyte-Derived CD11b+ Dendritic Cells Initiate and Maintain T Helper 2 Cell-Mediated Immunity to House Dust Mite Allergen

Maud Plantinga, Martin Guilliams, Manon Vanheerswynghels et al. · Immunity · 2013 · 875 citations · Full text

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G12-G13–LARG–mediated signaling in vascular smooth muscle is required for salt-induced hypertension

Angela Wirth, Zoltán Benyó, Martina Lukasova et al. · Nature Medicine · 2007 · 685 citations

, , +16

The experimental power of FR900359 to study Gq-regulated biological processes

Ramona Schrage, Anna-Lena Schmitz, Evelyn Gaffal et al. · Nature Communications · 2015 · 372 citations · Full text

, , +12

Bronchodilator action of inhaled nitric oxide in guinea pigs.

Patricia Dupuy, Stephanie A. Shore, Jeffrey M. Drazen et al. · Journal of Clinical Investigation · 1992 · 324 citations · Full text

, , +14

Deconvolution of complex G protein–coupled receptor signaling in live cells using dynamic mass redistribution measurements

R Schröder, Nicole Janssen, Johannes Schmidt et al. · Nature Biotechnology · 2010 · 258 citations

, , +16