Concepedia

LncRNA TUG1 sponges miR-204-5p to promote osteoblast differentiation through upregulating Runx2 in aortic valve calcification

Yu Cong, Lifu Li, Fei Xie, Shichao Guo, Fayuan Liu, Nianguo Dong, Yongjun Wang

Cardiovascular Research · 2017 · 250 citations · 37 references

DOI

Abstract

All together, the evidence generated by our study elucidates the role of lncRNA TUG1 as a miRNA sponge in CAVD, and sheds new light on lncRNA-directed diagnostics and therapeutics in CAVD.

References

37

An integrated encyclopedia of DNA elements in the human genome

Nature · 2012 · 18.9K citations · Full text

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A ceRNA Hypothesis: The Rosetta Stone of a Hidden RNA Language?

Leonardo Salmena, Laura Poliseno, Yvonne Tay et al. · Cell · 2011 · 7.6K citations · Full text

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The GENCODE v7 catalog of human long noncoding RNAs: Analysis of their gene structure, evolution, and expression

Thomas Derrien, Rory Johnson, Giovanni Bussotti et al. · Genome Research · 2012 · 5.1K citations · Full text

Human RISC Couples MicroRNA Biogenesis and Posttranscriptional Gene Silencing

Richard I. Gregory, Thimmaiah P. Chendrimada, Neil Cooch et al. · Cell · 2005 · 1.6K citations · Full text

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The STAT3-Binding Long Noncoding RNA lnc-DC Controls Human Dendritic Cell Differentiation

Pin Wang, Yiquan Xue, Yanmei Han et al. · Science · 2014 · 1.1K citations

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