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Synthesis and evaluation of asymmetric curcuminoid analogs as potential anticancer agents that downregulate NF-κB activation and enhance the sensitivity of gastric cancer cell lines to irinotecan chemotherapy

Medicinal ChemistryChemoprevention StrategyGastrointestinal OncologyMedicineTumor ImmunityIrinotecan ChemotherapyAsymmetric Curcuminoid AnalogsTumor TargetingAnti-cancer AgentCancer TreatmentNf-κb ActivationPharmacologyRadiation OncologyTumor BiologyDrug Discovery