Soluble Extracellular Domain of Death Receptor 5 Inhibits TRAIL-Induced Apoptosis by Disrupting Receptor–Receptor Interactions

Treatment of rheumatoid arthritis with tumor necrosis factor inhibitors may predispose to significant increase in tuberculosis risk: A multicenter active‐surveillance report

Juan J. Gómez‐Reino, Loreto Carmona, Vicente Rodríguez Valverde et al. · Arthritis & Rheumatism · 2003 · 1K citations

Medicine, Internal Medicine, Pharmacotherapy +15

Apo2L/TRAIL-Dependent Recruitment of Endogenous FADD and Caspase-8 to Death Receptors 4 and 5

Frank Kischkel, David A. Lawrence, Anan Chuntharapai et al. · Immunity · 2000 · 973 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

Tumor necrosis factor antagonist therapy and lymphoma development: Twenty‐six cases reported to the Food and Drug Administration

S Brown, Mark H. Greene, Sharon K. Gershon et al. · Arthritis & Rheumatism · 2002 · 661 citations

Life Sciences, Immunology, Pharmacotherapy +11

Fas Preassociation Required for Apoptosis Signaling and Dominant Inhibition by Pathogenic Mutations

Richard M. Siegel, John K. Frederiksen, David A. Zacharias et al. · Science · 2000 · 645 citations

Life Sciences, Cell Biology, Molecular Biology +17

Small-Molecule Inhibition of TNF-α

Molly M. He, Annemarie Stroustrup, Johan D. Oslob et al. · Science · 2005 · 598 citations

Life Sciences, Medicinal Chemistry, Pharmacology +17