Concepedia

Direct Activation of NADPH Oxidase 2 by 2-Deoxyribose-1-Phosphate Triggers Nuclear Factor Kappa B-Dependent Angiogenesis

Dina Vara, Joanna M. Watt, Tiago M. Fortunato, Matthew Burgess, Kate Wicks, Kimberly A. Mace, Shaun B. Reeksting, Anneke Lubben, Caroline Wheeler‐Jones, Giordano Pula

Antioxidants and Redox Signaling · 2017 · 37 citations · 56 references

DOIFull text

Open access

Abstract

This study describes a novel molecular mechanism underlying the proangiogenic activity of dRP, which involves the sequential activation of NOX2 and NF-κB and upregulation of VEGFR2. Antioxid. Redox Signal. 28, 110-130.

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