Science Signaling · 2017 · 20 citations · 44 references
Life SciencesCell BiologyImmunologyHepatologyInnate ImmunitySignal TransductionHepatic ImpairmentHepatic PathophysiologyInflammatory SignalingLiver DiseaseMetabolic Liver DiseaseToll-like ReceptorsHepatic Inflammatory InjuryHepatocellular Injury MechanismsHigh-fat Diet-induced Liver InjuryInflammatory Signaling In HepatocytesToll-like Receptor SignalingToll-like Receptor Signaling PathwaysToll-like Receptors In InflammationTrif-dependent Signaling
promoter. These results suggest an unconventional metabolic function for TLR/TRIF signaling that should be taken into consideration when seeking to pharmacologically inhibit this pathway.
44