Exogenous serotonin regulates colorectal motility via the 5‐<scp>HT</scp>₂ and 5‐<scp>HT</scp>₃ receptors in the spinal cord of rats

Abstract

These results demonstrate that exogenous serotonin acts on 5-HT₂ and 5-HT₃ receptors in the lumbosacral defecation center and activates the parasympathetic nervous system to enhance colorectal motility in cooperation with noradrenaline and dopamine.