Mechanisms of the hypoglycaemic and immunopotentiating effects of Nigella sativa L. oil in streptozotocin-induced diabetic hamsters

Khalid Fararh, Yasuro Atoji, Yasutake Shimizu, +3

Research in Veterinary Science

L. OilMedicineDiabetesGlycobiologyPhysiology +7

Thymoquinone reduces hepatic glucose production in diabetic hamsters

Khalid Fararh, Yasutake Shimizu, Takahiko Shiina, +3

Research in Veterinary Science

Metabolic SyndromeHepatic Glucose ProductionMedicineLiver PhysiologyPhysiology +6

Successful abrogation by thymoquinone against induction of diabetes mellitus with streptozotocin via nitric oxide inhibitory mechanism

Abubakr El-Mahmoudy, Yasutake Shimizu, Takahiko Shiina, +3

International Immunopharmacology

Diabetes ManagementMedicineInsulin ManagementDiabetesDiabetes Mellitus +2

Macrophage-derived cytokine and nitric oxide profiles in type I and type II diabetes mellitus: effect of thymoquinone

Abubakr El-Mahmoudy, Yasutake Shimizu, Takahiko Shiina, +3

Acta Diabetologica

InflammationMetabolic SyndromeAutoimmune DiseaseDiabetesImmunology +6

Targeted Disruption of MAIL, a Nuclear IκB Protein, Leads to Severe Atopic Dermatitis-like Disease

Takahiko Shiina, Akihiro Konno, Toshina Oonuma, +5

Journal of Biological Chemistry

Inhibitory effects of zingerone, a pungent component of Zingiber officinale Roscoe, on colonic motility in rats

Momoe Iwami, Takahiko Shiina, Haruko Hirayama, +3

Journal of Natural Medicines

Inhibitory EffectsGastrointestinal PharmacologyMedicineGastroenterologyDigestive Tract +3

Contrasting effects of ghrelin and des-acyl ghrelin on the lumbo-sacral defecation center and regulation of colorectal motility in rats

Haruko Hirayama, Takahiko Shiina, T Shima, +4

Neurogastroenterology & Motility

Involvement of TRPV1-dependent and -independent components in the regulation of vagally induced contractions in the mouse esophagus

Ammar Boudaka, Jürgen Wörl, Takahiko Shiina, +4

European Journal of Pharmacology

-Independent ComponentsInduced ContractionsSignal TransductionMolecular PhysiologyEsophagus +5

Stimulation of dopamine D2‐like receptors in the lumbosacral defaecation centre causes propulsive colorectal contractions in rats

Kiyotada Naitou, Hiroyuki Nakamori, Takahiko Shiina, +9

The Journal of Physiology

Hibernation-specific alternative splicing of the mRNA encoding cold-inducible RNA-binding protein in the hearts of hamsters

Yuuki Sano, Takahiko Shiina, Kiyotada Naitou, +2

Biochemical and Biophysical Research Communications

Systems BiologyEngineeringCold-inducible Rna-binding ProteinRna Binding ProteinsPhysiology +8