Chloroquine-induced scratching is mediated by NO/cGMP pathway in mice

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Life Sciences, Neurobiology, Neuroscience +14

Sildenafil: an orally active type 5 cyclic GMP-specific phosphodiesterase inhibitor for the treatment of penile erectile dysfunction.

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Medicine, Pharmacology, Pharmacotherapy +10

Sensory Neuron-Specific GPCR Mrgprs Are Itch Receptors Mediating Chloroquine-Induced Pruritus

Qin Liu, Zongxiang Tang, Lenka Surdenikova et al. · Cell · 2009 · 808 citations · Full text

Life Sciences, Neuroscience, Pharmacology +10

TRPA1 is required for histamine-independent, Mas-related G protein–coupled receptor–mediated itch

Sarah R. Wilson, Kristin A. Gerhold, Amber Bifolck-Fisher et al. · Nature Neuroscience · 2011 · 605 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +8