Experimental Modeling Supports a Role for MyBP-HL as a Novel Myofilament Component in Arrhythmia and Dilated Cardiomyopathy

Abstract

The findings of reduced ventricular function and conduction system defects in <i>Mybphl</i> mice support that <i>MYBPHL</i> truncations may increase risk for human arrhythmias and cardiomyopathy.