Contribution of vascular endothelial growth factor receptor-2 sialylation to the process of angiogenesis

The elderberry (Sambucus nigra L.) bark lectin recognizes the Neu5Ac(alpha 2-6)Gal/GalNAc sequence.

Naoto Shibuya, Irwin Goldstein, W. F. Broekaert et al. · Journal of Biological Chemistry · 1987 · 788 citations · Full text

Life Sciences, Biochemistry, Botany +16

Glycosylation-Dependent Lectin-Receptor Interactions Preserve Angiogenesis in Anti-VEGF Refractory Tumors

Diego O. Croci, Juan P. Cerliani, Tomás Dalotto‐Moreno et al. · Cell · 2014 · 499 citations · Full text

Medicine, Cancer Biology, Oncology +14

The immobilized leukoagglutinin from the seeds of Maackia amurensis binds with high affinity to complex-type Asn-linked oligosaccharides containing terminal sialic acid-linked alpha-2,3 to penultimate galactose residues.

Wen‐Ching Wang, Richard D. Cummings · Journal of Biological Chemistry · 1988 · 455 citations · Full text

Life Sciences, Biochemistry, Microbiology +17

The 230 kDa mature form of KDR/Flk-1 (VEGF receptor-2) activates the PLC-γ pathway and partially induces mitotic signals in NIH3T3 fibroblasts

Tomoko Takahashi, Masabumi Shibuya · Oncogene · 1997 · 308 citations

Life Sciences, Cell Biology, Molecular Biology +9

The interaction of Neuropilin-1 with Vascular Endothelial Growth Factor and its receptor Flt-1

Germaine Fuh · Journal of Biological Chemistry · 2000 · 285 citations

Life Sciences, Biochemistry, Molecular Biology +11