The interaction of Neuropilin-1 with Vascular Endothelial Growth Factor and its receptor Flt-1

Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice

Fouad Shalaby, Janet Rossant, Terry P. Yamaguchi et al. · Nature · 1995 · 3.9K citations

Medicine, Cell Biology, Pathology +8

Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium

Guo‐Hua Fong, Janet Rossant, Marina Gertsenstein et al. · Nature · 1995 · 2.6K citations

Life Sciences, Cell Biology, Molecular Biology +13

Neuropilin-1 Is Expressed by Endothelial and Tumor Cells as an Isoform-Specific Receptor for Vascular Endothelial Growth Factor

Shay Söker, Seiji Takashima, Hua Miao et al. · Cell · 1998 · 2.5K citations · Full text

Medicine, Cancer Biology, Oncology +15

High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis

B Millauer, Susanne Wizigmann-Voos, Harald Schnürch et al. · Cell · 1993 · 1.9K citations

Life Sciences, Cell Biology, Developmental Biology +16

Different signal transduction properties of KDR and Flt1, two receptors for vascular endothelial growth factor.

Johannes Waltenberger, Lena Claesson‐Welsh, Agneta Siegbahn et al. · Journal of Biological Chemistry · 1994 · 1.7K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13