Phenolic Compounds from Orostachys japonicus having Anti - HIV-1 Protease Activity

Abstract

The water extract of the aerial parts of Orostachys japonicus A. Berger showed the inhibitory activity against HIV-1 protease. From the same parts of O. japonicus, 4-hydroxybenzoic acid, 3,4-dihydroxybenzoic acid, gallic acid and methyl gallate, together with flavonoids, kaempferol, quercetin, kaempferol 3-O-β-D-glucoside, kaempferol 3-O-β-D-galactoside and quercetin 3-O-β-D-glucoside were isolated and characterized by spectral data.