The HLF/IL-6/STAT3 feedforward circuit drives hepatic stellate cell activation to promote liver fibrosis - Concepedia

Concepedia

Publication | Closed Access

The HLF/IL-6/STAT3 feedforward circuit drives hepatic stellate cell activation to promote liver fibrosis

220

Citations

33

References

2017

Year

Daimin Xiang, Wen Sun, Beifang Ning, Tengfei Zhou, Xiaofeng Li, Wei Zhong, Zhuo Cheng, Mingyang Xia, Xue Wang, Xing Deng,

Abstract

In aggregate, we delineate a paradigm of HLF/IL-6/STAT3 regulatory circuit in liver fibrosis and propose that HLF is a novel biomarker for activated HSCs and a potential target for antifibrotic therapy.

References

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