Concepedia

Untargeted DNA-Demethylation Therapy Neither Prevents Nor Attenuates Ischemia-Reperfusion-Induced Renal Fibrosis

Benjamin A. Vervaet, Lies Moonen, Lode Godderis, Katrien Poels, Patrick C. D’Haese

˜The œNephron journals/Nephron journals · 2017 · 12 citations · 28 references

DOI

Abstract

Administration of untargeted nucleoside analogues seems unsuitable as a first-line treatment option in developing or established CKD.

References

28

Genome-wide Methylation Profiles Reveal Quantitative Views of Human Aging Rates

Gregory Hannum, Justin Guinney, Ling Zhao et al. · Molecular Cell · 2012 · 4.2K citations · Full text

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Origin and function of myofibroblasts in kidney fibrosis

Valerie S. LeBleu, Gangadhar Taduri, Joyce T. O’Connell et al. · Nature Medicine · 2013 · 1.2K citations · Full text

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Methylation determines fibroblast activation and fibrogenesis in the kidney

Wibke Bechtel‐Walz, Scott McGoohan, Elisabeth M. Zeisberg et al. · Nature Medicine · 2010 · 615 citations · Full text

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Impact of inflammation on epigenetic DNA methylation – a novel risk factor for cardiovascular disease?

Peter Stenvinkel, Mohsen Karimi, Stefan Johansson et al. · Journal of Internal Medicine · 2007 · 401 citations · Full text

Association between enhanced type I collagen expression and epigenetic repression of the <i>FLI1</i> gene in scleroderma fibroblasts

Youngqing Wang, Pan‐Sheng Fan, Bashar Kahaleh · Arthritis & Rheumatism · 2006 · 341 citations