Synlett · 2017 · 76 citations · 12 references
Natural SciencesChemistryMedicinal ChemistryCatalysisOrganic ChemistrySynthetic Medicinal ChemistryCatalyst DesignCatalytic MaterialsCatalytic MechanismsHeterocycle SynthesisHeterocyclic ChemistryOrganic SynthesisAlkyne Cycloaddition ReactionsIndole ChemistryIndole DerivativesIndole SynthesisMetal CatalystsTransition Metal CatalystsTransition Metal-catalyzed SynthesisTransition-metal-catalyzed Heterocycle Synthesis
The oxidative [3+2] cycloaddition of alkynes with arylamines is a powerful method for the synthesis of (aza)indoles because it employs unfunctionalized and easily available materials. Herein, recent progress in the synthesis of (aza)indoles through transition metal-catalyzed oxidative [3+2] cycloaddition is highlighted. 1 Introduction 2 Second-Row Transition-Metal Catalysts 3 First-Row Transition-Metal Catalysts 4 Summary
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