Palladium‐Catalyzed Oxidative Cyclization of <i>N</i>‐Aryl Enamines: From Anilines to Indoles

Abstract

The special advantage of the title reaction to form substituted indoles 2 lies within the broad scope of the transformation: A multitude of N-aryl enaminones 1 can be prepared readily in one step from commercially available anilines. Furthermore, anilines can be converted directly in a one-pot process into the indole products. R1=H, Me, OMe, Cl, F, carbonyl functionality, CN, fused aryl; R2=alkyl, aryl; R3=alkyl, Oalkyl. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2008/z802482_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.