An Ullmann N-arylation/2-amidation cascade by self-relay copper catalysis: one-pot synthesis of indolo[1,2-a]quinazolinones

Abstract

We have developed a self-relay copper(<sc>i</sc>)-catalyzed Ullmann <italic>N</italic>-arylation/2-amidation cascade to form functionalized indolo[1,2-<italic>a</italic>]quinazolinones in one-pot from easily available indoles with 2-bromobenzamides.