A Simple and Efficient Approach to Quinazolinones under Mild Copper‐Catalyzed Conditions

Abstract

Cop some rings: A simple and highly efficient copper-catalyzed method for the synthesis of quinazolinone derivatives through the reaction of substituted 2-halobenzoic acids with amidines or guanidines under mild conditions has been developed (see scheme). The method has economical and practical advantages.