New prodrugs of two pyrimidine acyclic nucleoside phosphonates: Synthesis and antiviral activity

Alkoxyalkyl prodrugs of acyclic nucleoside phosphonates enhance oral antiviral activity and reduce toxicity: Current state of the art

Karl Y. Hostetler · Antiviral Research · 2009 · 235 citations · Full text

Alkoxyalkyl Prodrugs, Oral Antiviral Activity, Medicinal Chemistry +12

Structure−Antiviral Activity Relationship in the Series of Pyrimidine and Purine <i>N</i>-[2-(2-Phosphonomethoxy)ethyl] Nucleotide Analogues. 1. Derivatives Substituted at the Carbon Atoms of the Base

Jaroslav Günter, Hana Dvořáková, Milena Masojı́dková et al. · Journal of Medicinal Chemistry · 1999 · 165 citations · Full text

Bioorganic Chemistry, Engineering, Organic Chemistry +18

Synthesis, Oral Bioavailability Determination, and in vitro Evaluation of Prodrugs of the Antiviral Agent 9-[2-(Phosphonomethoxy)ethyl]adenine (PMEA)

John E. Starrett, David R. Tortolani, Michael J. M. Hitchcock et al. · Journal of Medicinal Chemistry · 1994 · 141 citations

6-[2-(Phosphonomethoxy)alkoxy]pyrimidines with Antiviral Activity

Ivan Votruba, Milena Masojı́dková, Graciela Andreï et al. · Journal of Medicinal Chemistry · 2002 · 138 citations

5-Substituted-2,4-diamino-6-[2-(phosphonomethoxy)ethoxy]pyrimidinesAcyclic Nucleoside Phosphonate Analogues with Antiviral Activity

Dana Hocková, Milena Masojı́dková, Graciela Andreï et al. · Journal of Medicinal Chemistry · 2003 · 102 citations