TBAB-catalyzed cascade reactions: facile synthesis of 1-trifluoromethyl-3-alkylidene-1,3-dihydrofuro[3,4-b]quinolines via 5-exo-dig cyclization of o-arylalkynylquinoline aldehydes

Abstract

TBAB-catalyzed cascade reaction condition is developed for the synthesis of 1-trifluoromethyl-3-alkylidene-1,3-dihydrofuro[3,4-<italic>b</italic>]quinolines from<italic>o</italic>-arylalkynylquinoline aldehydes<italic>via</italic>5-<italic>exo</italic>-dig cyclization.