PubMed · 2009 · 24 citations · 20 references
MedicinePharmacologyToxicologyBehavioral PharmacologyExperimental PharmacologyGeneral PharmacologyAnimal Models In PharmacologyBehavioral ToxicologyConcentration-effect RelationshipsDose-response RelationshipsAnimal Model EvaluationAnimal Model PharmacologyBehavioral ExperimentsBehavioral Pharmacology AssaysBehavioral Pharmacology ModelsDrug Concentration-effect RelationshipResearch Experiences For UndergraduatesToxicity In Animals
In this work we describe a series of simple protocols using planaria as an animal model in toxicology and behavioral pharmacology. These procedures have proven useful to provide significant research experience to undergraduate students, including coauthorship in peer-reviewed publications. The methods described in this work have proven useful to allow students to visualize concepts related to concentration-effect curves for toxicity and behavioral experiments, without the need to consider factors that must be taken into account when working with vertebrate animals.
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The Hill equation revisited: uses and misuses
James N. Weiss · The FASEB Journal · 1997 · 1K citations
Robert B. Raffa, Lauren J Holland, Robert Schulingkamp · Journal of Pharmacological and Toxicological Methods · 2001 · 99 citations