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Structural basis for selective inhibition of Cyclooxygenase-1 (COX-1) by diarylisoxazoles mofezolac and 3-(5-chlorofuran-2-yl)-5-methyl-4-phenylisoxazole (P6)

Selective InhibitionMedicinal ChemistryHeterocyclicBiochemistryNatural SciencesMedicineMechanism Of ActionStructural BasisPharmacotherapyAnti-cancer AgentHeterocycle ChemistryChemical BiologyPharmacologyPharmaceutical ChemistryDrug DiscoveryDiarylisoxazoles MofezolacDrug Resistance