Detecting selection signatures between Duroc and Duroc synthetic pig populations using high‐density <scp>SNP</scp> chip

Abstract

Summary The development of high throughput genotyping techniques has facilitated the identification of selection signatures of pigs. The detection of genomic selection signals in a population subjected to differential selection pressures may provide insights into the genes associated with economically and biologically important traits. To identify genomic regions under selection, we genotyped 488 Duroc (D) pigs and 155 D × Korean native pigs ( DKNP s) using the Porcine SNP 70K BeadChip. By applying the F ST and extended haplotype homozygosity ( EHH ‐Rsb) methods, we detected genes under directional selection associated with growth/stature ( DOCK 7 , PLCB 4 , HS 2 ST 1 , FBP 2 and TG ), carcass and meat quality ( TG , COL 14A1 , FBXO 5 , NR 3C1 , SNX 7 , ARHGAP 26 and DPYD ), number of teats ( LOC 100153159 and LRRC 1 ), pigmentation ( MME ) and ear morphology ( SOX 5 ), which are all mostly near or at fixation. These results could be a basis for investigating the underlying mutations associated with observed phenotypic variation. Validation using genome‐wide association analysis would also facilitate the inclusion of some of these markers in genetic evaluation programs.